منابع مشابه
Mitochondrial Medicine and the Neurodegenerative Mitochondriopathies
Neurodegenerative diseases are a common late-life scourge for which disease-modifying treatments are sorely needed. Mitochondrial perturbation is commonly observed in these diseases, so pursuing treatment development strategies that target mitochondria or processes affected by mitochondria seems reasonable. This review discusses the rationale underlying past and current efforts to treat neurode...
متن کاملP 155: The Roles of Microglia in Neurodegenerative Diseases
Microglia is a type of glial cell located throughout the central nervous system (CNS), which is sensitive to CNS injury and disease. Responsibility of microglia as the resident macrophage cells for injuries suggests that these cells have the potential to act as diagnostic markers of disease beginning or progression. Function of Microglia is strongly synchronized by the microenvironment of brain...
متن کاملP152: Neurotoxicants and Mechanisms Neurodegenerative in Acrylamide
Many chemicals with broad industrial, pharmaceutical and agricultural application produce a neurotoxic syndrome in humans and experimental animals involving weight loss, skeletal muscle weakness and ataxia. Neurotoxicity is defined as a structural change or a functional alteration of the nervous system resulting from exposure to a chemical, biological or physical agent. Neurotoxicity including ...
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ژورنال
عنوان ژورنال: Journal of Alzheimer's Disease
سال: 2009
ISSN: 1875-8908,1387-2877
DOI: 10.3233/jad-2009-1095